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Drug spotlight, Celecoxib from G. D. Searle Company

April 9, 2013

New Drug Approvals

Celecoxib3Dan.gif

File:Celecoxib.svg

CELECOXIB

4-[5-(4- methylphenyl)-3-(trifluoromethyl)-lH-pyrazol-l-yl]benzenesulfonamide

169590-42-5

Celebrex, Celebra, Celocoxib, Onsenal, YM177
Molecular Formula:C17H14F3N3O2S
Molecular Weight:381.37217 g/mol

mp…157-159 deg C

O’Neil, M.J. (ed.). The Merck Index – An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 336
US5563165*PED; 5760068; 5466823*PED; 5563165; RE44048; 5760068*PED; 5466823; RE44048*PED (from FDA Orange Book)
Celecoxib is a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, acute pain, painful menstruation and menstrual symptoms, and to reduce numbers of colon and rectum polyps in patients with familial adenomatous polyposis. It is marketed by Pfizer under the brand name Celebrex. In some countries, it is branded Celebra. Celecoxib is available by prescription in capsule form.from DrugBank [2]
Celecoxib is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of celecoxib is as…

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