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March 21, 2013

New Drug Approvals

recombinant human FGF-18


Darmstadt, Germany, March 18, 2013 –

Merck Serono, a division of Merck in Darmstadt, Germany, today announced a strategic alliance with Nordic Bioscience Clinical Development A/S on Merck Serono’s investigational drug sprifermin (recombinant human FGF-18) in osteoarthritis (OA) of the knee. This agreement underscores Merck Serono’s commitment to osteoarthritis research and development.

Under the terms of the agreement, Nordic Bioscience will provide clinical development services to Merck Serono on a shared-risk basis in exchange for a payment structure that includes service fees and potential milestone and royalty payments on the program. Merck Serono retains full responsibility for the development and commercialization of the investigational drug. Financial terms of the collaboration were not disclosed. The alliance will draw on the joint expertise and resources of Merck Serono and Nordic Bioscience to conduct a multi-national Phase IIb trial (the FORWARD study) to further evaluate sprifermin for inhibition of…

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